Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

 		Prostate Cancer Phase3 Australia
China
Japan
Singapore
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 NCT06855277

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

 		Glomerulonephritis, IGA, Immunoglobulin A Nephropathy Phase2 Malaysia
United States 		NCT06797518

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

 		Chronic Spontaneous Urticaria (CSU) Phase3 United States NCT06868212

A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

 		Prostatic Cancer, Castration-Resistant Phase2 Australia
Israel
Singapore
United States
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 NCT07047118

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

 		Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD) Phase1, Phase2 France
Germany
Singapore
Spain
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 NCT07048197

An Ascending Dose Study of PIT565 in Participants With Rheumatoid Arthritis

 		Rheumatoid Arthritis Phase1 China
Germany
Netherlands
Romania
Spain
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 NCT07029555

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

 		Atherosclerotic Cardiovascular Disease Russia NCT06858332

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study

 		Atherosclerotic Vascular Disease, Heterozygous Familial Hypercholesterolemia Spain NCT06958315

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

 		Atherosclerotic Cardiovascular Disease (ASCVD) Phase3 China
Hong Kong
Puerto Rico
United Kingdom
United States
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 NCT06813911

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

 		Hematologic Malignancy, Solid Tumor, Advanced Malignancies Phase3 Belgium
Italy
Netherlands
United Kingdom
United States
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 NCT06401356