Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV Steroid-refractory Acute Graft vs. Host Disease

 		Steroid-refractory Acute Graft Versus Host Disease Phase4 China NCT06462469

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

 		Breast Cancer Phase1, Phase2 Australia
Canada
China
France
Germany
Italy
Netherlands
Portugal
Singapore
South Korea
Spain
United Kingdom
United States
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 NCT06247995

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

 		Aortic Stenosis Phase2 Austria
Belgium
Canada
Czechia
Denmark
France
Germany
Israel
Italy
Netherlands
Portugal
Spain
Switzerland
United Kingdom
United States
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 NCT05646381

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

 		Relapsing Multiple Sclerosis Phase3 Argentina
Brazil
Bulgaria
Canada
China
Croatia
Estonia
France
Greece
India
Italy
Japan
Mexico
Poland
Portugal
Puerto Rico
Romania
Slovakia
Slovenia
South Africa
Spain
Sweden
Turkey (Türkiye)
United Kingdom
United States
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 NCT05156281

Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan

 		Prostate Cancer Phase2 Japan NCT05114746

Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma

 		Newly Diagnosed and Recurrent Glioblastoma Phase1 France
Germany
Israel
Italy
Portugal
Spain
United Kingdom
United States
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 NCT05739942

Real-world Experience With Lutetium Vipivotide Tetraxetan in Metastatic Castration Resistant Prostate Cancer

 		Metastatic Castration Resistant Prostate Cancer Germany NCT06517719

Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

 		C3G Phase3 Brazil
Canada
China
France
Germany
Greece
India
Israel
Italy
Japan
Netherlands
Spain
Switzerland
Turkey (Türkiye)
United Kingdom
United States
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 NCT04817618

Study of PIK3CA Mutations and Effectiveness and Tolerability Outcomes of Alpelisib in Real-world

 		Breast Cancer India NCT05022342

A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis

 		Multiple Sclerosis Germany NCT06551519